Correction of ornithine accumulation prevents retinal degeneration in a mouse model of gyrate atrophy of the choroid and retina

Eitemau Tebyg

• A mouse model of gyrate atrophy of the choroid and retina. Early retinal pigment epithelium damage and progressive retinal degeneration.
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• An initiator codon mutation in ornithine-delta-aminotransferase causing gyrate atrophy of the choroid and retina.
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• Ornithine ketoacid transaminase deficiency in gyrate atrophy of the choroid and retina.
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• Gyrate atrophy of the choroid and retina
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