Correction of ornithine accumulation prevents retinal degeneration in a mouse model of gyrate atrophy of the choroid and retina

Deficiency of ornithine-δ-aminotransferase (OAT) in humans results in gyrate atrophy of the choroid and retina (GA), an autosomal recessive disorder characterized by ornithine accumulation and a progressive chorioretinal degeneration of unknown pathogenesis. To determine whether chronic, systemic re...

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Bibliografski detalji

Izdano u:	Proc Natl Acad Sci U S A
Glavni autori:	Wang, Tao, Steel, Gary, Milam, Ann H., Valle, David
Format:	Artigo
Jezik:	Inglês
Izdano:	National Academy of Sciences 2000
Teme:	Biological Sciences
Online pristup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15576/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10655512/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.3.1224
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