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Correction of ornithine accumulation prevents retinal degeneration in a mouse model of gyrate atrophy of the choroid and retina

Deficiency of ornithine-δ-aminotransferase (OAT) in humans results in gyrate atrophy of the choroid and retina (GA), an autosomal recessive disorder characterized by ornithine accumulation and a progressive chorioretinal degeneration of unknown pathogenesis. To determine whether chronic, systemic re...

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Xehetasun bibliografikoak
Egile Nagusiak: Wang, Tao, Steel, Gary, Milam, Ann H., Valle, David
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The National Academy of Sciences 2000
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC15576/
https://ncbi.nlm.nih.gov/pubmed/10655512
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