Correction of ornithine accumulation prevents retinal degeneration in a mouse model of gyrate atrophy of the choroid and retina

Deficiency of ornithine-δ-aminotransferase (OAT) in humans results in gyrate atrophy of the choroid and retina (GA), an autosomal recessive disorder characterized by ornithine accumulation and a progressive chorioretinal degeneration of unknown pathogenesis. To determine whether chronic, systemic re...

Fuld beskrivelse

Bibliografiske detaljer

Udgivet i:	Proc Natl Acad Sci U S A
Principais autores:	Wang, Tao, Steel, Gary, Milam, Ann H., Valle, David
Format:	Artigo
Sprog:	Inglês
Udgivet:	National Academy of Sciences 2000
Fag:	Biological Sciences
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15576/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10655512/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.3.1224
Tags:	Tilføj Tag Ingen Tags, Vær først til at tagge denne postø!