In vivo treatment with a monoclonal chimeric anti-CD4 antibody results in prolonged depletion of circulating CD4(+) cells in chimpanzees

Chimeric M-T412 (cM-T412), an anti-CD4 antibody, was tolerated in chimpanzees at a dosage of 5 mg/kg per day for up to 7 consecutive days, or 5 mg/kg per dose, twice weekly for 4 weeks. All cM-T412-treated chimpanzees showed a prolonged CD4 cell depression. Weak chimpanzee antibody responses to chim...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Jonker, M., Slingerland, W., Treacy, G., van Eerd, P., Pak, K. Y., Wilson, E., Tam, S., Bakker, K., Lobuglio, A. F., Rieber, P., Riethmuller, G., Daddona, P. E., Iuliucci, J.
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Assuntos:
Experimental Immunotherapy
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1554916/
https://ncbi.nlm.nih.gov/pubmed/8103714
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados