In vivo depletion of CD4(+)CD25(+) regulatory T cells in cats

To establish a characterized model of regulatory T cell (Treg) depletion in the cat we assessed the kinetics of depletion and rebound in peripheral and central lymphoid compartments after treatment with anti-CD25 antibody as determined by cell surface markers and FOXP3 mRNA expression. An 82% decrea...

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Autores principales: Smithberg, S. Rochelle, Fogle, Jonathan E., Mexas, Angela M., Reckling, Stacie K., Lankford, Susan M., Tompkins, Mary B., Dean, Gregg A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2007
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2246310/
https://ncbi.nlm.nih.gov/pubmed/17980384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2007.09.015
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