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In vivo depletion of CD4(+)CD25(hi) regulatory T cells is associated with improved antiviral responses in cats chronically infected with feline immunodeficiency virus

Regulatory T (Treg) cells are activated and suppress immune responses during infection, and are characterized as CD4(+)CD25(hi)FOXP3(+). Ex vivo studies demonstrate that Treg cells potentially suppress anti-HIV-1 T cell responses. Lentivirus-induced CD4(+)CD25(hi) Treg cells were first described in...

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Detalhes bibliográficos
Main Authors: Mikkelsen, S Rochelle, Reckling, Stacie K, Egan, Erin A, Dean, Gregg A
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2879469/
https://ncbi.nlm.nih.gov/pubmed/20471053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2010.04.016
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