A cellular antidote to specifically deplete anti-CD19 chimeric antigen receptor–positive cells

Unintentional transduction of B-cell acute lymphoblastic leukemia blasts during CART19 manufacturing can lead to CAR19(+) leukemic cells (CARB19) that are resistant to CART19 killing. We developed an anti-CAR19 idiotype chimeric antigen receptor (αCAR19) to specifically recognize CAR19(+) cells. αCA...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Blood
Egile Nagusiak: Ruella, Marco, Barrett, David M., Shestova, Olga, Perazzelli, Jessica, Posey, Avery D., Hong, Seok Jae, Kozlowski, Miroslaw, Lacey, Simon F., Melenhorst, J. Joseph, June, Carl H., Gill, Saar I.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Hematology 2020
Gaiak:
Immunobiology and Immunotherapy
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7019191/
https://ncbi.nlm.nih.gov/pubmed/31703119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019001859
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak