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A cellular antidote to specifically deplete anti-CD19 chimeric antigen receptor–positive cells
Unintentional transduction of B-cell acute lymphoblastic leukemia blasts during CART19 manufacturing can lead to CAR19(+) leukemic cells (CARB19) that are resistant to CART19 killing. We developed an anti-CAR19 idiotype chimeric antigen receptor (αCAR19) to specifically recognize CAR19(+) cells. αCA...
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| Publicado no: | Blood |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7019191/ https://ncbi.nlm.nih.gov/pubmed/31703119 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019001859 |
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