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A novel role for Xist RNA in the formation of a repressive nuclear compartment into which genes are recruited when silenced
During early mammalian female development, one of the two X chromosomes becomes inactivated. Although X-chromosome coating by Xist RNA is essential for the initiation of X inactivation, little is known about how this signal is transformed into transcriptional silencing. Here we show that exclusion o...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , |
|---|---|
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Cold Spring Harbor Laboratory Press
2006
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1553206/ https://ncbi.nlm.nih.gov/pubmed/16912274 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.380906 |
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