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Protein Tyrosine Phosphatase 1B Attenuates Growth Hormone-Mediated JAK2-STAT Signaling

Protein tyrosine phosphatase-1B (PTP-1B) attenuates insulin, PDGF, EGF, and IGF-I signaling by dephosphorylating tyrosine residues located in the tyrosine kinase domain of the corresponding receptors. More recently, PTP-1B was shown to modulate the action of cytokine signaling via the nonreceptor ty...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Gu, Feng, Dubé, Nadia, Kim, Jin Wook, Cheng, Alan, Ibarra-Sanchez, Maria de Jesus, Tremblay, Michel L., Boisclair, Yves R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2003
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC155228/
https://ncbi.nlm.nih.gov/pubmed/12748279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.11.3753-3762.2003
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