Glycoprotein I of Varicella-Zoster Virus Is Required for Viral Replication in Skin and T Cells

Varicella-zoster virus (VZV) glycoprotein I (gI) is dispensable in cell culture; the SCIDhu model of VZV pathogenesis was used to determine whether gI is necessary in vivo. The parental and repaired viruses grew in human skin and thymus/liver implants, but the gI deletion mutant was not infectious....

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Moffat, Jennifer, Ito, Hideki, Sommer, Marvin, Taylor, Shannon, Arvin, Ann M.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2002
Assuntos:	Pathogenesis and Immunity
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC155157/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12134050/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.16.8468-8471.2002
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