Mutational Analysis of Open Reading Frames 62 and 71, Encoding the Varicella-Zoster Virus Immediate-Early Transactivating Protein, IE62, and Effects on Replication In Vitro and in Skin Xenografts in the SCID-hu Mouse In Vivo

The varicella-zoster virus (VZV) genome has unique long (U(L)) and unique short (U(S)) segments which are flanked by internal repeat (IR) and terminal repeat (TR) sequences. The immediate-early 62 (IE62) protein, encoded by open reading frame 62 (ORF62) and ORF71 in these repeats, is the major VZV t...

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Autors principals: Sato, Bunji, Ito, Hideki, Hinchliffe, Stewart, Sommer, Marvin H., Zerboni, Leigh, Arvin, Ann M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2003
Matèries:
Replication
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC154054/
https://ncbi.nlm.nih.gov/pubmed/12719553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.10.5607-5620.2003
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