Mutations of the RNase H C Helix of the Moloney Murine Leukemia Virus Reverse Transcriptase Reveal Defects in Polypurine Tract Recognition

Both the RNase H domain of Moloney murine leukemia virus (Mo-MLV) reverse transcriptase (RT) and Escherichia coli RNase H possess a positively charged α-helix (C helix) and a loop that are not present in the RNase H domains of human immunodeficiency virus (HIV) RT or avian sarcoma virus RT. Although...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Lim, David, Orlova, Marianna, Goff, Stephen P.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2002
Témata:
Replication
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC155118/
https://ncbi.nlm.nih.gov/pubmed/12134040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.16.8360-8373.2002
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky