Cre Levels Limit Packaging Signal Excision Efficiency in the Cre/loxP Helper-Dependent Adenoviral Vector System

Helper-dependent (HD) adenovirus vectors devoid of all viral coding sequences have a large cloning capacity and provide long-term transgene expression in vivo with negligible toxicity, making them attractive vectors for gene therapy. Currently, the most efficient means of producing HD vectors involv...

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Podrobná bibliografie

Vydáno v:	J Virol
Hlavní autoři:	Ng, Philip, Evelegh, Carole, Cummings, Derek, Graham, Frank L.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 2002
Témata:	Gene Therapy
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC155107/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11932383/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.9.4181-4189.2002
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