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A helper-dependent system for adenovirus vector production helps define a lower limit for efficient DNA packaging.
Adenoviruses (Ads) are intermediate-sized mammalian DNA viruses with a double-stranded linear genome of 36 kb. The icosohedral virion has been shown to accommodate up to 105% of the wild-type genome length, and genomes larger than this size are either unpackageable or extremely unstable, frequently...
Wedi'i Gadw mewn:
Prif Awduron: | , |
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Fformat: | Artigo |
Iaith: | Inglês |
Cyhoeddwyd: |
1997
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Pynciau: | |
Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC191467/ https://ncbi.nlm.nih.gov/pubmed/9060698 |
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