A helper-dependent system for adenovirus vector production helps define a lower limit for efficient DNA packaging.
Adenoviruses (Ads) are intermediate-sized mammalian DNA viruses with a double-stranded linear genome of 36 kb. The icosohedral virion has been shown to accommodate up to 105% of the wild-type genome length, and genomes larger than this size are either unpackageable or extremely unstable, frequently...
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| Publicado no: | J Virol |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
1997
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191467/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9060698/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.4.3293-3298.1997 |
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