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Functional role of inward rectifier current in heart probed by Kir2.1 overexpression and dominant-negative suppression
The inward rectifier current I(K1) is tightly regulated regionally within the heart, downregulated in heart failure, and genetically suppressed in Andersen syndrome. We used in vivo viral gene transfer to dissect the role of I(K1) in cardiac repolarization and maintenance of the resting membrane pot...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Clinical Investigation
2003
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC155052/ https://ncbi.nlm.nih.gov/pubmed/12750402 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200317959 |
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