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Functional role of inward rectifier current in heart probed by Kir2.1 overexpression and dominant-negative suppression

The inward rectifier current I(K1) is tightly regulated regionally within the heart, downregulated in heart failure, and genetically suppressed in Andersen syndrome. We used in vivo viral gene transfer to dissect the role of I(K1) in cardiac repolarization and maintenance of the resting membrane pot...

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Hlavní autoři: Miake, Junichiro, Marbán, Eduardo, Nuss, H. Bradley
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC155052/
https://ncbi.nlm.nih.gov/pubmed/12750402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200317959
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