Kir2.1 Interactome Mapping Uncovers PKP4 as a Modulator of the Kir2.1-Regulated Inward Rectifier Potassium Currents

Kir2.1, a strong inward rectifier potassium channel encoded by the KCNJ2 gene, is a key regulator of the resting membrane potential of the cardiomyocyte and plays an important role in controlling ventricular excitation and action potential duration in the human heart. Mutations in KCNJ2 result in in...

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Detalhes bibliográficos
Publicado no:Mol Cell Proteomics
Main Authors: Park, Sung-Soo, Ponce-Balbuena, Daniela, Kuick, Rork, Guerrero-Serna, Guadalupe, Yoon, Justin, Mellacheruvu, Dattatreya, Conlon, Kevin P., Basrur, Venkatesha, Nesvizhskii, Alexey I., Jalife, José, Rual, Jean-François
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8143648/
https://ncbi.nlm.nih.gov/pubmed/32541000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA120.002071
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