Kir2.1 Interactome Mapping Uncovers PKP4 as a Modulator of the Kir2.1-Regulated Inward Rectifier Potassium Currents

Kir2.1, a strong inward rectifier potassium channel encoded by the KCNJ2 gene, is a key regulator of the resting membrane potential of the cardiomyocyte and plays an important role in controlling ventricular excitation and action potential duration in the human heart. Mutations in KCNJ2 result in in...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Cell Proteomics
Egile Nagusiak: Park, Sung-Soo, Ponce-Balbuena, Daniela, Kuick, Rork, Guerrero-Serna, Guadalupe, Yoon, Justin, Mellacheruvu, Dattatreya, Conlon, Kevin P., Basrur, Venkatesha, Nesvizhskii, Alexey I., Jalife, José, Rual, Jean-François
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2020
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8143648/
https://ncbi.nlm.nih.gov/pubmed/32541000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA120.002071
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