Ras activation in response to phorbol ester proceeds independently of the EGFR via an unconventional nucleotide-exchange factor system in COS-7 cells

Ras is a major mediator of PE (phorbol ester) effects in mammalian cells. Various mechanisms for PE activation of Ras have been reported [Downward, Graves, Warne, Rayter and Cantrell (1990) Nature (London) 346, 719–723; Shu, Wu, Mosteller and Broek (2002) Mol. Cell. Biol. 22, 7758–7768; Roose, Molle...

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Главные авторы: Rubio, Ignacio, Rennert, Knut, Wittig, Ute, Beer, Katrin, Dürst, Matthias, Stang, Stacey L., Stone, Jim, Wetzker, Reinhard
Формат: Artigo
Язык:Inglês
Опубликовано: Portland Press Ltd. 2006
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1550314/
https://ncbi.nlm.nih.gov/pubmed/16709153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20060160
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