Direct stimulation of Vav guanine nucleotide exchange activity for Ras by phorbol esters and diglycerides.

We recently identified Vav as a Ras-activating guanine nucleotide exchange factor (GEF) stimulated by a T-cell antigen receptor-coupled protein tyrosine kinase (PTK). Here, we describe a novel, protein kinase-independent alternative pathway of Vav activation. Phorbol ester, 1,2-diacylglycerol, or ce...

Disgrifiad llawn

Manylion Llyfryddiaeth

Cyhoeddwyd yn:	Mol Cell Biol
Prif Awduron:	Gulbins, E, Coggeshall, K M, Baier, G, Telford, D, Langlet, C, Baier-Bitterlich, G, Bonnefoy-Berard, N, Burn, P, Wittinghofer, A, Altman, A
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Taylor & Francis 1994
Pynciau:	Research Article
Mynediad Ar-lein:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC358848/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7516472/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.7.4749-4758.1994
Tagiau:	Ychwanegu Tag Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!