Direct stimulation of Vav guanine nucleotide exchange activity for Ras by phorbol esters and diglycerides.

We recently identified Vav as a Ras-activating guanine nucleotide exchange factor (GEF) stimulated by a T-cell antigen receptor-coupled protein tyrosine kinase (PTK). Here, we describe a novel, protein kinase-independent alternative pathway of Vav activation. Phorbol ester, 1,2-diacylglycerol, or ce...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Gulbins, E, Coggeshall, K M, Baier, G, Telford, D, Langlet, C, Baier-Bitterlich, G, Bonnefoy-Berard, N, Burn, P, Wittinghofer, A, Altman, A
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1994
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC358848/
https://ncbi.nlm.nih.gov/pubmed/7516472
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi