Live-cell imaging of endogenous Ras-GTP illustrates predominant Ras activation at the plasma membrane

Ras-GTP imaging studies using the Ras-binding domain (RBD) of the Ras effector c-Raf as a reporter for overexpressed Ras have produced discrepant results about the possible activation of Ras at the Golgi apparatus. We report that RBD oligomerization provides probes for visualization of endogenous Ra...

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Bibliografski detalji
Glavni autori: Augsten, Martin, Pusch, Rico, Biskup, Christoph, Rennert, Knut, Wittig, Ute, Beyer, Katja, Blume, Alfred, Wetzker, Reinhard, Friedrich, Karlheinz, Rubio, Ignacio
Format: Artigo
Jezik:Inglês
Izdano: 2006
Teme:
Scientific Report
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1369223/
https://ncbi.nlm.nih.gov/pubmed/16282985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400560
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