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Identification of three crucial histidine residues (His(115), His(132) and His(297)) in porcine deoxyribonuclease II
DNase II is an acid endonuclease that is involved in the degradation of exogenous DNA and is important for DNA fragmentation and degradation during cell death. In an effort to understand its catalytic mechanism, we constructed plasmids encoding nine different histidine (H)-to-leucine (L) mutants for...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Portland Press Ltd.
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1550313/ https://ncbi.nlm.nih.gov/pubmed/16734590 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20060564 |
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