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Identification of three crucial histidine residues (His(115), His(132) and His(297)) in porcine deoxyribonuclease II

DNase II is an acid endonuclease that is involved in the degradation of exogenous DNA and is important for DNA fragmentation and degradation during cell death. In an effort to understand its catalytic mechanism, we constructed plasmids encoding nine different histidine (H)-to-leucine (L) mutants for...

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Bibliografische gegevens
Hoofdauteurs: Cheng, Yu-Che, Hsueh, Chin-Chen, Lu, Shao-Chun, Liao, Ta-Hsiu
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Portland Press Ltd. 2006
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1550313/
https://ncbi.nlm.nih.gov/pubmed/16734590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20060564
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