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Identification of three crucial histidine residues (His(115), His(132) and His(297)) in porcine deoxyribonuclease II

DNase II is an acid endonuclease that is involved in the degradation of exogenous DNA and is important for DNA fragmentation and degradation during cell death. In an effort to understand its catalytic mechanism, we constructed plasmids encoding nine different histidine (H)-to-leucine (L) mutants for...

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書誌詳細
主要な著者: Cheng, Yu-Che, Hsueh, Chin-Chen, Lu, Shao-Chun, Liao, Ta-Hsiu
フォーマット: Artigo
言語:Inglês
出版事項: Portland Press Ltd. 2006
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1550313/
https://ncbi.nlm.nih.gov/pubmed/16734590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20060564
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