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Forced unfolding of the fibronectin type III module reveals a tensile molecular recognition switch
The 10th type III module of fibronectin possesses a β-sandwich structure consisting of seven β-strands (A–G) that are arranged in two antiparallel sheets. It mediates cell adhesion to surfaces via its integrin binding motif, Arg(78), Gly(79), and Asp(80) (RGD), which is placed at the apex of the loo...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC15466/ https://ncbi.nlm.nih.gov/pubmed/9990027 |
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