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Structure and functional significance of mechanically unfolded fibronectin type III(1) intermediates

Fibronectin (FN) forms fibrillar networks coupling cells to the extracellular matrix. The formation of FN fibrils, fibrillogenesis, is a tightly regulated process involving the exposure of cryptic binding sites in individual FN type III (FN-III) repeats presumably exposed by mechanical tension. The...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Gao, Mu, Craig, David, Lequin, Olivier, Campbell, Iain D., Vogel, Viola, Schulten, Klaus
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2003
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC299803/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14657397/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.2334390100
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