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Comparison of the early stages of forced unfolding for fibronectin type III modules

The structural changes accompanying stretch-induced early unfolding events were investigated for the four type III fibronectin (FN-III) modules, FN-III(7), FN-III(8), FN-III(9), and FN-III(10) by using steered molecular dynamics. Simulations revealed that two main energy barriers, I and II, have to...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Craig, David, Krammer, André, Schulten, Klaus, Vogel, Viola
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2001
Schlagworte:
Biological Sciences
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC33257/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11331785/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.101582198
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