Forced unfolding of the fibronectin type III module reveals a tensile molecular recognition switch

The 10th type III module of fibronectin possesses a β-sandwich structure consisting of seven β-strands (A–G) that are arranged in two antiparallel sheets. It mediates cell adhesion to surfaces via its integrin binding motif, Arg(78), Gly(79), and Asp(80) (RGD), which is placed at the apex of the loo...

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Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Krammer, André, Lu, Hui, Isralewitz, Barry, Schulten, Klaus, Vogel, Viola
Materialtyp: Artigo
Språk:Inglês
Publicerad: The National Academy of Sciences 1999
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC15466/
https://ncbi.nlm.nih.gov/pubmed/9990027
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