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Regulation of RAG1/RAG2-mediated transposition by GTP and the C-terminal region of RAG2

The RAG1 and RAG2 proteins perform critical DNA recognition and cleavage functions in V(D)J recombination, and also catalyze efficient DNA transposition in vitro. No transposition in vivo by the RAG proteins has been reported, suggesting regulation of the reaction by as yet unknown mechanisms. Here...

詳細記述

保存先:
書誌詳細
主要な著者: Tsai, Chia-Lun, Schatz, David G.
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2003
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC154477/
https://ncbi.nlm.nih.gov/pubmed/12682024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg185
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