Regulation of RAG1/RAG2-mediated transposition by GTP and the C-terminal region of RAG2

The RAG1 and RAG2 proteins perform critical DNA recognition and cleavage functions in V(D)J recombination, and also catalyze efficient DNA transposition in vitro. No transposition in vivo by the RAG proteins has been reported, suggesting regulation of the reaction by as yet unknown mechanisms. Here...

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Vydáno v:	EMBO J
Hlavní autoři:	Tsai, Chia-Lun, Schatz, David G.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Publishing Group 2003
Témata:	Articles
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC154477/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12682024/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg185
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