Human prions and plasma lipoproteins

Prions are composed solely of an alternatively folded isoform of the prion protein (PrP), designated PrP(Sc). The polyoxometalate phosphotungstic acid has been used to separate PrP(Sc) from its precursor PrP(C) by selective precipitation; notably, native PrP(Sc) has not been solubilized by using non...

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Autori principali: Safar, Jiri G., Wille, Holger, Geschwind, Michael D., Deering, Camille, Latawiec, Diane, Serban, Ana, King, David J., Legname, Giuseppe, Weisgraber, Karl H., Mahley, Robert W., Miller, Bruce L., DeArmond, Stephen J., Prusiner, Stanley B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2006
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1544083/
https://ncbi.nlm.nih.gov/pubmed/16849426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0604021103
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