Modulation of p47(PHOX) activity by site-specific phosphorylation: Akt-dependent activation of the NADPH oxidase
The leukocyte NADPH oxidase catalyzes the reduction of oxygen to O [Formula: see text] at the expense of NADPH. Extensive phosphorylation of the oxidase subunit p47(PHOX) occurs during the activation of the enzyme in intact cells. p47(PHOX) carrying certain serine-to-alanine mutations fails to suppo...
Uloženo v:
| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2003
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC154310/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12704229/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1031526100 |
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