ATM is a cytoplasmic protein in mouse brain required to prevent lysosomal accumulation

We previously generated a mouse model with a mutation in the murine Atm gene that recapitulates many aspects of the childhood neurodegenerative disease ataxia-telangiectasia. Atm-deficient (Atm−/−) mice show neurological defects detected by motor function tests including the rota-rod, open-field tes...

Descrizione completa

Dettagli Bibliografici

Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Barlow, Carrolee, Ribaut-Barassin, Catherine, Zwingman, Theresa A., Pope, Amber J., Brown, Kevin D., Owens, Jennie W., Larson, Denise, Harrington, Elizabeth A., Haeberle, Anne-Marie, Mariani, Jean, Eckhaus, Michael, Herrup, Karl, Bailly, Yannick, Wynshaw-Boris, Anthony
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 2000
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15423/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10639172/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.2.871
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!