Attenuation of Mycobacterium tuberculosis by Disruption of a mas-Like Gene or a Chalcone Synthase-Like Gene, Which Causes Deficiency in Dimycocerosyl Phthiocerol Synthesis

Tuberculosis is one of the leading preventable causes of death. Emergence of drug-resistant tuberculosis makes the discovery of new targets for antimycobacterial drugs critical. The unique mycobacterial cell wall lipids are known to play an important role in pathogenesis, and therefore the genes res...

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Dettagli Bibliografici

Pubblicato in:	J Bacteriol
Autori principali:	Sirakova, Tatiana D., Dubey, Vinod S., Cynamon, Michael H., Kolattukudy, Pappachan E.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2003
Soggetti:	Molecular Biology of Pathogens
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC154080/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12730158/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JB.185.10.2999-3008.2003
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