Attenuation of Mycobacterium tuberculosis by Disruption of a mas-Like Gene or a Chalcone Synthase-Like Gene, Which Causes Deficiency in Dimycocerosyl Phthiocerol Synthesis

Tuberculosis is one of the leading preventable causes of death. Emergence of drug-resistant tuberculosis makes the discovery of new targets for antimycobacterial drugs critical. The unique mycobacterial cell wall lipids are known to play an important role in pathogenesis, and therefore the genes res...

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Bibliografiske detaljer

Udgivet i:	J Bacteriol
Principais autores:	Sirakova, Tatiana D., Dubey, Vinod S., Cynamon, Michael H., Kolattukudy, Pappachan E.
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 2003
Fag:	Molecular Biology of Pathogens
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC154080/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12730158/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JB.185.10.2999-3008.2003
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