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Attenuation of Mycobacterium tuberculosis by Disruption of a mas-Like Gene or a Chalcone Synthase-Like Gene, Which Causes Deficiency in Dimycocerosyl Phthiocerol Synthesis

Tuberculosis is one of the leading preventable causes of death. Emergence of drug-resistant tuberculosis makes the discovery of new targets for antimycobacterial drugs critical. The unique mycobacterial cell wall lipids are known to play an important role in pathogenesis, and therefore the genes res...

詳細記述

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書誌詳細
出版年:J Bacteriol
主要な著者: Sirakova, Tatiana D., Dubey, Vinod S., Cynamon, Michael H., Kolattukudy, Pappachan E.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 2003
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC154080/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12730158/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JB.185.10.2999-3008.2003
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