In Vivo Evolution of Human Immunodeficiency Virus Type 1 toward Increased Pathogenicity through CXCR4-Mediated Killing of Uninfected CD4 T Cells

The destruction of the immune system by progressive loss of CD4 T cells is the hallmark of AIDS. CCR5-dependent (R5) human immunodeficiency virus type 1 (HIV-1) isolates predominate in the early, asymptomatic stages of HIV-1 infection, while CXCR4-dependent (X4) isolates typically emerge at later st...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Jekle, Andreas, Keppler, Oliver T., De Clercq, Erik, Schols, Dominique, Weinstein, Mark, Goldsmith, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC154038/
https://ncbi.nlm.nih.gov/pubmed/12719578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.10.5846-5854.2003
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados