Viral Entry through CXCR4 Is a Pathogenic Factor and Therapeutic Target in Human Immunodeficiency Virus Type 1 Disease

The chemokine receptors CCR5 and CXCR4 function as the principal coreceptors for human immunodeficiency virus type 1 (HIV-1). Coreceptor function has also been demonstrated for a variety of related receptors in vitro. The relative contributions of CCR5, CXCR4, and other putative coreceptors to HIV-1...

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Detalhes bibliográficos
Main Authors: Schramm, Birgit, Penn, Michael L., Speck, Roberto F., Chan, Stephen Y., De Clercq, Erik, Schols, Dominique, Connor, Ruth I., Goldsmith, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC111527/
https://ncbi.nlm.nih.gov/pubmed/10590105
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