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Comparison of Adjuvant Efficacy of Herpes Simplex Virus Type 1 Recombinant Viruses Expressing T(H)1 and T(H)2 Cytokine Genes

The adjuvant effects of cytokines in humoral and cell-mediated immunity to herpes simplex virus type 1 (HSV-1) have been examined in mice using HSV-1 recombinant viruses expressing murine interleukin-2 (IL-2), IL-4, or gamma interferon (IFN-γ) gene. Groups of naive BALB/c mice were immunized intrape...

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Detalhes bibliográficos
Main Authors: Osorio, Yanira, Ghiasi, Homayon
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC154018/
https://ncbi.nlm.nih.gov/pubmed/12719570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.10.5774-5783.2003
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