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Recombinant Herpes Simplex Virus Type 1 (HSV-1) Codelivering Interleukin-12p35 as a Molecular Adjuvant Enhances the Protective Immune Response against Ocular HSV-1 Challenge

An important aspect of ocular herpes simplex virus type 1 (HSV-1) vaccine development is identification of an appropriate adjuvant capable of significantly reducing both virus replication in the eye and explant reactivation in trigeminal ganglia. We showed recently that a recombinant HSV-1 vaccine e...

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Bibliografische gegevens
Hoofdauteurs: Osorio, Yanira, Ghiasi, Homayon
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2005
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1075685/
https://ncbi.nlm.nih.gov/pubmed/15731224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.6.3297-3308.2005
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