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Inhibition of Protease-Resistant Prion Protein Accumulation In Vitro by Curcumin
Inhibition of the accumulation of protease-resistant prion protein (PrP-res) is a prime strategy in the development of potential transmissible spongiform encephalopathy (TSE) therapeutics. Here we show that curcumin (diferoylmethane), a major component of the spice turmeric, potently inhibits PrP-re...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology
2003
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC153975/ https://ncbi.nlm.nih.gov/pubmed/12692251 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.9.5499-5502.2003 |
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