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Immunogenicity and Protective Immunity against Bubonic Plague and Pneumonic Plague by Immunization of Mice with the Recombinant V10 Antigen, a Variant of LcrV

In contrast to Yersinia pestis LcrV, the recombinant V10 (rV10) variant (lacking residues 271 to 300) does not suppress the release of proinflammatory cytokines by immune cells. Immunization with rV10 generates robust antibody responses that protect mice against bubonic plague and pneumonic plague,...

詳細記述

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書誌詳細
主要な著者: DeBord, Kristin L., Anderson, Deborah M., Marketon, Melanie M., Overheim, Katie A., DePaolo, R. William, Ciletti, Nancy A., Jabri, Bana, Schneewind, Olaf
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2006
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1539636/
https://ncbi.nlm.nih.gov/pubmed/16861680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01860-05
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