Immunogenicity and Protective Immunity against Bubonic Plague and Pneumonic Plague by Immunization of Mice with the Recombinant V10 Antigen, a Variant of LcrV

In contrast to Yersinia pestis LcrV, the recombinant V10 (rV10) variant (lacking residues 271 to 300) does not suppress the release of proinflammatory cytokines by immune cells. Immunization with rV10 generates robust antibody responses that protect mice against bubonic plague and pneumonic plague,...

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Bibliografiset tiedot
Päätekijät: DeBord, Kristin L., Anderson, Deborah M., Marketon, Melanie M., Overheim, Katie A., DePaolo, R. William, Ciletti, Nancy A., Jabri, Bana, Schneewind, Olaf
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2006
Aiheet:
Microbial Immunity and Vaccines
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1539636/
https://ncbi.nlm.nih.gov/pubmed/16861680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01860-05
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