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Additional Conjugation Methods and Immunogenicity of Bacillus anthracis Poly-γ-d-Glutamic Acid-Protein Conjugates
The capsule of Bacillus anthracis, composed of poly-γ-d-glutamic acid (γDPGA), is an essential virulence factor of B. anthracis. The capsule inhibits innate host defense through its antiphagocytic action. γDPGA is a poor immunogen, but when covalently bound to a carrier protein, it elicits serum ant...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Microbiology
2006
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1539631/ https://ncbi.nlm.nih.gov/pubmed/16861662 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00315-06 |
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