Additional Conjugation Methods and Immunogenicity of Bacillus anthracis Poly-γ-d-Glutamic Acid-Protein Conjugates

The capsule of Bacillus anthracis, composed of poly-γ-d-glutamic acid (γDPGA), is an essential virulence factor of B. anthracis. The capsule inhibits innate host defense through its antiphagocytic action. γDPGA is a poor immunogen, but when covalently bound to a carrier protein, it elicits serum ant...

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Bibliografiska uppgifter
Huvudupphovsmän: Kubler-Kielb, Joanna, Liu, Teh-Yung, Mocca, Christopher, Majadly, Fathy, Robbins, John B., Schneerson, Rachel
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2006
Ämnen:
Microbial Immunity and Vaccines
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1539631/
https://ncbi.nlm.nih.gov/pubmed/16861662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00315-06
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