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Effect of the nonreducing end of Shigella dysenteriae type 1 O-specific oligosaccharides on their immunogenicity as conjugates in mice

Endemic and epidemic shigellosis, an acute invasive disease of the lower intestines, afflicts millions of people worldwide with an estimated one million fatalities per annum at a low infectious dose. Our approach to vaccine development against Shigella is based on the hypothesis that serum IgG antib...

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Main Authors: Pozsgay, Vince, Kubler-Kielb, Joanna, Schneerson, Rachel, Robbins, John B.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1955462/
https://ncbi.nlm.nih.gov/pubmed/17726093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0706969104
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