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Synthesis, characterization, and immunogenicity in mice of Shigella sonnei O-specific oligosaccharide-core-protein conjugates

Shigellosis, an enteric disease, is on the World Health Organization's priority prevention list. In one study, the Shigella sonnei O-specific polysaccharide (O-SP)-protein conjugate showed 72% protection against disease in Israeli army recruits exposed to high rates (8–14%) of infection. The pr...

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Detalhes bibliográficos
Main Authors: Robbins, John B., Kubler-Kielb, Joanna, Vinogradov, Evguenii, Mocca, Christopher, Pozsgay, Vince, Shiloach, Joseph, Schneerson, Rachel
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2683083/
https://ncbi.nlm.nih.gov/pubmed/19346477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0900891106
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