Endogenous phosphatidylcholine and a long spacer ligand stabilize the lipid-binding groove of CD1b

CD1 proteins present lipid antigens to T cells. The antigens are acquired in the endosomal compartments. This raises the question of how the large hydrophobic CD1 pockets are preserved between the moment of biosynthesis in the endoplasmic reticulum and arrival to the endosomes. To address this issue...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Garcia-Alles, Luis F, Versluis, Kees, Maveyraud, Laurent, Vallina, Ana Tesouro, Sansano, Sebastiano, Bello, Nana Fatimath, Gober, Hans-Jürgen, Guillet, Valérie, de la Salle, Henri, Puzo, Germain, Mori, Lucia, Heck, Albert J R, De Libero, Gennaro, Mourey, Lionel
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2006
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1538567/
https://ncbi.nlm.nih.gov/pubmed/16874306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601244
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg