Crystal structure of human CD1e reveals a groove suited for lipid-exchange processes

CD1e is the only human CD1 protein existing in soluble form in the late endosomes of dendritic cells, where it facilitates the processing of glycolipid antigens that are ultimately recognized by CD1b-restricted T cells. The precise function of CD1e remains undefined, thus impeding efforts to predict...

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Detalhes bibliográficos
Main Authors: Garcia-Alles, Luis F., Giacometti, Gaelle, Versluis, Cees, Maveyraud, Laurent, de Paepe, Diane, Guiard, Julie, Tranier, Samuel, Gilleron, Martine, Prandi, Jacques, Hanau, Daniel, Heck, Albert J. R., Mori, Lucia, De Libero, Gennaro, Puzo, Germain, Mourey, Lionel, de la Salle, Henri
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3156185/
https://ncbi.nlm.nih.gov/pubmed/21788486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1105627108
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