Crystal structure of human CD1e reveals a groove suited for lipid-exchange processes

CD1e is the only human CD1 protein existing in soluble form in the late endosomes of dendritic cells, where it facilitates the processing of glycolipid antigens that are ultimately recognized by CD1b-restricted T cells. The precise function of CD1e remains undefined, thus impeding efforts to predict...

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Bibliografski detalji
Glavni autori: Garcia-Alles, Luis F., Giacometti, Gaelle, Versluis, Cees, Maveyraud, Laurent, de Paepe, Diane, Guiard, Julie, Tranier, Samuel, Gilleron, Martine, Prandi, Jacques, Hanau, Daniel, Heck, Albert J. R., Mori, Lucia, De Libero, Gennaro, Puzo, Germain, Mourey, Lionel, de la Salle, Henri
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2011
Teme:
Biological Sciences
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3156185/
https://ncbi.nlm.nih.gov/pubmed/21788486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1105627108
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