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Evidence that the retroviral DNA integration process triggers an ATR-dependent DNA damage response
Caffeine is an efficient inhibitor of cellular DNA repair, likely through its effects on ATM (ataxia telangiectasia mutated) and ATR (ATM and Rad3-related) kinases. Here, we show that caffeine treatment causes a dose-dependent reduction in the total amount of HIV-1 and avian sarcoma virus retroviral...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC153632/ https://ncbi.nlm.nih.gov/pubmed/12679521 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0730887100 |
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