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Filamin-A fragment localizes to the nucleus to regulate androgen receptor and coactivator functions
The androgen receptor (AR), a nuclear transcription factor, mediates male sexual differentiation, and its excessive action is associated with prostate cancer. We have characterized a negative regulatory domain in the AR hinge region, which interacted with filamin A (FLNa), an actin-binding cytoskele...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC153595/ https://ncbi.nlm.nih.gov/pubmed/12682292 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0736237100 |
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